Problem
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Matching 28-1
MATCH each of the following terms to a structure from
the list below. There is only one correct structure for each term and structures may be used more
than once. Place the letter of the structure in the blank to the left of the corresponding
term.
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1.
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Refer
to Matching 28-1. __________ DNA base sequence with cytosine at the 3' end.
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2.
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Refer
to Matching 28-1. __________ uridine
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3.
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Refer
to Matching 28-1. __________ a purine nucleoside
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Stolle Synthesis
Refer to the
data below to answer the following questions:
Indole derivatives may be synthesized by reaction of arylamines with
a-haloacid
chlorides followed by cyclization of the resulting amides with aluminum chloride in a process known
as the Stollé Synthesis.
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4.
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Refer
to Stolle Synthesis. Write the complete stepwise mechanism for the second step of the Stollé
Synthesis. Show all intermediate structures and all electron flow with arrows.
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5.
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Thiophene carboxylic acid derivatives may be prepared from 1,2-diketones and dialkyl
thiodiacetate.
Draw arrows indicating electron flow on the
intermediate structures provided below for the mechanism for this
reaction.
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6.
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Describe in general terms, the steps involved in the automated synthesis of the DNA
sequence GCT.
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7.
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Give
the major organic product(s) of the following reaction.
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8.
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Give
the major organic product(s) of the following reaction.
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9.
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Give
the major organic product(s) of the following reaction.
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10.
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Give
the major organic product(s) of the following reaction.
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