Chapter 20
Organic Chemistry
History and Scope
Early chemists believed that molecules derived from animal or plant sources were created by some "vital force". The vital source theory held that organic molecules could only come from living sources. In 1828 Friedrich Wöhler produced urea (H2N-CO-NH2), an organic molecule, from the reaction of cyanic acid (HCNO) and ammonia (NH3). Since both cyanic acid and ammonia can be produced from nonliving sources and urea is a product of the metabolism of animals, urea was the first organic molecule produced from nonliving source. This was the downfall of the vial force theory.
Classification of Organic Molecules
Organic molecules are classified by their "functional groups". A functional group is an atom or group of atoms bonded in a particular configuration.
Classes of organic molecules: "R" represents any hydrocarbon.
Alkane R-H
Alkene C=C with 2 H and/or C atoms bonded to each carbon
Alkyne C=C with 1 H or C atom bonded to each carbon
Alkyl halide R-X Where X is a halogen
Alcohol R-OH Alcohols have an -OH group somewhere in the molecule
Ether R-O-R' Ethers have an O bonded to two carbons
O
Aldehyde R-C-H Aldehydes have a double bonded O at the end of a chain
O
Keytone R-C-R Keytone have a double bonded O within a carbon chain
O
Carboxylic acid R-C-O-H Organic acids have a double bonded O and OH at end of chain
O O
Ester R-C-O-R' Esters have a -C-O group within the carbon chain
Think 3-D
The carbon atom makes 4 bonds with other atoms. Consider the following molecules:
H
H-C-H methane
H
Carbon with 4 atoms attached is tetrahedral.
H
C=O formaldehyde
H
Carbon with three atoms attached is trigonal planar.
O=C=O carbon dioxide
Carbon with two atoms attached is linear.
Most atoms in organic molecules always have the same number of bonds.
Atom Number of bonds Examples of bonding
Haolgens 1 F- Cl- Br- I-
Hydrogen 1 H-
Oxygen 2 O= -O-
Nitrogen 3 N= -N= -N-
Carbon 4 -C= =C= -C= -C-
When drawing organic molecules keep the above bonding numbers.
Alkanes CnH2n+2
Name Formula Condensed structural formula
Methane CH4
Ethane C2H6 CH3CH3
Propane C3H8 CH3CH2CH3
Butane C4H10 CH3CH2CH2CH3
Pentane C5H12 CH3CH2CH2CH2CH3
Hexane C6H14 CH3CH2CH2CH2CH2CH3
Heptane C7H16 CH3CH2CH2CH2CH2CH2CH3
Octane C8H18 CH3CH2CH2CH2CH2CH2CH2CH3
Nonane C9H20 CH3CH2CH2CH2CH2CH2CH2CH2CH3
Decane C10H22 CH3CH2CH2CH2CH2CH2CH2CH2CH2CH3
Structural Isomerism
Structural isomers have the same formula but different structures.
Problem:
How many different compounds can be made for butane C4H10?
Draw each compound.
Problem:
How many different compounds can be made for butane C5H12?
Draw each compound.
Organic Nomenclature
Substituent Formula Condensed structural formula
Bromo Br-
Chloro Cl-
Fluoro F-
Iodo I-
Methyl CH3-
Ethyl C2H5- CH3CH2-
Propyl C3H7- CH3CH2CH2-
Butyl C4H9- CH3CH2CH2CH2-
Pentyl C5H11- CH3CH2CH2CH2CH2-
Hexyl C6H13- CH3CH2CH2CH2CH2CH2-
Heptyl C7H15- CH3CH2CH2CH2CH2CH2CH2-
Octyl C8H17- CH3CH2CH2CH2CH2CH2CH2CH2-
Nonyl C9H19- CH3CH2CH2CH2CH2CH2CH2CH2CH2-
Decyl C10H21- CH3CH2CH2CH2CH2CH2CH2CH2CH2CH2-
Note: Just replace -ane with -yl to name a hydrocarbon as a substituent group.
To name many of the billions of organic compounds the following nomenclature rules can be used.
Alkane Reactions
Alkanes, as all hydrocarbons burn to give CO2 and H2O.
Alkanes undergo halogenation in the presence of ultraviolet light.
R-H + Cl2 ---> R-Cl + HCl
Demo:
Cyclohexane and bromine water light and no light.
Alkenes CnH2n and Alkynes CnH2n-2
Alkenes and alkynes are classified as unsaturated hydrocarbons because they do not contain the maximum number of hydrogens.
Nomenclature of Alkenes and Alkynes
To name an alkene name the position of the double bond in the carbon chain and change the ane to ene.
To name an alkyne the position of the triple bond in the carbon chain and change the ane to yne.
Reactions of Alkenes and Alkynes
Alkenes and Alkynes undergo hydrogenation.
CH=CH + H2 --Pt--> CH2=CH2
CH2=CH2 + H2 --Pt--> CH3CH3
Alkenes and Alkynes undergo halogenation.
CH=CH + Br2 ----> CHBr=CHBr
CH2=CH2 + Cl2 ----> CH2ClCH2Cl
Alkenes and Alkynes undergo hydrohalogenation.
CH=CH + HCl ----> CH2=CHCl
CH2=CH2 + HCl ----> CH3CH2Cl
Aromatic Compounds
Aromatic compounds are those compounds that have properties resembling benzene (C6H6). Although they have many double bonds, they do not react as do alkenes.
Nomenclature of Aromatics
Monosubstituted Benzenes
Name the substituent group followed by the word benzene. Some monosubstituted benzenes have special names. ie. methylbenzene = toluene
hydroxybenzene = phenol
analine
benzoic acid
benzaldehyde
When benzene is a substituent group (C6H5-) on another molecule it is named phenyl.
Disubstituted Benzene
Ortho means the two substituents are adjacent to eachother.
Meta means the two substituents are separated by one carbon.
Para means the two substituents are separated by two carbons.
Some disubstituted benzenes have special names such as xylene and come in three varieties: ortho-xylene, meta-xylene, para-xylene
Polysubstituted Benzenes
The benzene ring is numbered giving the lowest number to the functional group which gives may give the benzene a special name.
Alcohols
Alcohols have the -OH group.
Alcohol Nomenclature
Give the position of the -OH group on the carbon chain and change the ane ending to -ol
Reactions of Alcohols
Mild oxidation of primary alcohols gives aldehydes which can in turn be oxidized to acids.
CH3CH2OH --K2Cr2O7--> CH3CHO --K2Cr2O7--> CH3CO2H
Oxidation of secondary alcohols gives ketones.
CH3CHOHCH3 --KMnO4--> CH3COCH3
Alcohols react with active metals to form organometallic compounds and hydrogen much like the reaction between water and active metals.
2CH3CH2OH + 2Na ---> 2 CH3CH2ONa + H2
Ethers R-0-R'
Ethers are relatively unreactive.
Naming Ethers
The name of each substituent group followed by the word ether. (Not IUPAC)
Aldehydes RCHO
Aldehydes are given the name of the hydrocarbon changing the -ane ending to -al.
Ketones RCOR'
Ketones are named by giving the location of the oxygen on the carbon chain and changing the -ane ending to -one
Reaction of Aldehydes and Ketones
Aldehydes react with silver ion to form an acid ion and metallic silver.
Aldehydes and ketones react with hydrogen in the presence of Ni or Pt to form alcohols.
Organic Acids RCO2H and Esters RCO2R'
Organic acids tend to be weak acids but will react with strong bases.
Organic acids react with alcohols to form esters.
Polymers
The term polymer means many unit. There are many kinds of polymers each with its own properties and uses.
Demo:
Polymeric Balls
Demo:
Nylon 6-6